Cleaved-Aggrecan (D369) Polyclonal Antibody

产品详情

产品名称

Cleaved-Aggrecan (D369) Polyclonal Antibody

产品货号

YM-A03890

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,IHC,IF,ELISA

分子量

44kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Aggrecan. AA range:320-369

特异性

Cleaved-Aggrecan (D369) Polyclonal Antibody detects endogenous levels of fragment of activated Aggrecan protein resulting from cleavage adjacent to D369.

基因名称

ACAN

蛋白名称

Aggrecan core protein

别名

ACAN;AGC1;CSPG1;MSK16;Aggrecan core protein;Cartilage-specific proteoglycan core protein;CSPCP;Chondroitin sulfate proteoglycan core protein 1;Chondroitin sulfate proteoglycan 1

基因ID-1

176

SwissProt

P16112

背景

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008],

细胞定位

Secreted, extracellular space, extracellular matrix .