Cleaved-CD97β (S531) Polyclonal Antibody

产品详情

产品名称

Cleaved-CD97β (S531) Polyclonal Antibody

产品货号

YM-A03896

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA

分子量

34kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human CD97 beta. AA range:512-561

特异性

Cleaved-CD97β (S531) Polyclonal Antibody detects endogenous levels of fragment of activated CD97β protein resulting from cleavage adjacent to S531.

基因名称

CD97

蛋白名称

CD97 antigen

别名

CD97;CD97 antigen;Leukocyte antigen CD97;CD antigen CD97

基因ID-1

976

SwissProt

P48960

背景

This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 1

细胞定位

Cell membrane ; Multi-pass membrane protein .; [Adhesion G protein-coupled receptor E5 subunit alpha]: Secreted, extracellular space .