Cleaved-Ephrin-A2 (N188) Polyclonal Antibody

产品详情

产品名称

Cleaved-Ephrin-A2 (N188) Polyclonal Antibody

产品货号

YM-A03900

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

21kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human EFNA2. AA range:139-188

特异性

Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188.

基因名称

EFNA2

蛋白名称

Ephrin-A2

别名

EFNA2;EPLG6;LERK6;Ephrin-A2;EPH-related receptor tyrosine kinase ligand 6;LERK-6;HEK7 ligand;HEK7-L

基因ID-1

1943

SwissProt

O43921

背景

This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Lipid-anchor, GPI-anchor .