Cleaved-KLK11 (I54) Polyclonal Antibody

产品详情

产品名称

Cleaved-KLK11 (I54) Polyclonal Antibody

产品货号

YM-A03903

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA

分子量

25kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Kallikrein-11. AA range:35-84

特异性

Cleaved-KLK11 (I54) Polyclonal Antibody detects endogenous levels of fragment of activated KLK11 protein resulting from cleavage adjacent to I54.

基因名称

KLK11

蛋白名称

Kallikrein-11

别名

KLK11;PRSS20;TLSP;Kallikrein-11;hK11;Hippostasin;Serine protease 20;Trypsin-like protease

基因ID-1

11012

SwissProt

Q9UBX7

背景

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009],

细胞定位

[Isoform 1]: Secreted.; [Isoform 2]: Golgi apparatus.