Cleaved-PAR-4 (G48) Polyclonal Antibody

产品详情

产品名称

Cleaved-PAR-4 (G48) Polyclonal Antibody

产品货号

YM-A03920

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA

分子量

33kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PAR4. AA range:29-78

特异性

Cleaved-PAR-4 (G48) Polyclonal Antibody detects endogenous levels of fragment of activated PAR-4 protein resulting from cleavage adjacent to G48.

基因名称

F2RL3

蛋白名称

Proteinase-activated receptor 4

别名

F2RL3;PAR4;Proteinase-activated receptor 4;PAR-4;Coagulation factor II receptor-like 3;Thrombin receptor-like 3

基因ID-1

9002

SwissProt

Q96RI0

背景

This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016],

细胞定位

Cell membrane; Multi-pass membrane protein.