MMP-1 Polyclonal Antibody

产品详情

产品名称

MMP-1 Polyclonal Antibody

产品货号

YM-A03946

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,ELISA

分子量

55kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from MMP-1 . at AA range: 190-270

特异性

MMP-1 Polyclonal Antibody detects endogenous levels of MMP-1 protein.

基因名称

MMP1

蛋白名称

Interstitial collagenase

别名

MMP1;CLG;Interstitial collagenase;Fibroblast collagenase;Matrix metalloproteinase-1;MMP-1

基因ID-1

4312

SwissProt

P03956

背景

matrix metallopeptidase 1(MMP1) Homo sapiens This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],

细胞定位

Secreted, extracellular space, extracellular matrix .