FA9 (heavy chain, Cleaved-Val227) rabbit pAb

产品详情

产品名称

FA9 (heavy chain, Cleaved-Val227) rabbit pAb

产品货号

YM-A03974

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

27kD,45kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:1000-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human FA9 (heavy chain, Cleaved-Val227)

特异性

This antibody detects endogenous levels of Human,Mouse,Rat FA9 (heavy chain, Cleaved-Val227, protein was cleaved amino acid sequence between 226-227 )

基因名称

F9 Factor IX

蛋白名称

FA9 (heavy chain, Cleaved-Val227)

别名

Coagulation factor IX;Christmas factor;Plasma thromboplastin component;PTC;[Cleaved into: Coagulation factor IXa light chain;Coagulation factor IXa heavy chain]

基因ID-1

2158

SwissProt

P00740

背景

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015],

细胞定位

Secreted .