ENTK (light chain, Cleaved-Ile785) rabbit pAb

产品详情

产品名称

ENTK (light chain, Cleaved-Ile785) rabbit pAb

产品货号

YM-A03999

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA

分子量

26kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:1000-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human ENTK (light chain, Cleaved-Ile785)

特异性

This antibody detects endogenous levels of Human ENTK (light chain, Cleaved-Ile785, protein was cleaved amino acid sequence between 785-786 )

基因名称

TMPRSS15 ENTK PRSS7

蛋白名称

ENTK (light chain, Cleaved-Ile785)

别名

Enteropeptidase;Enterokinase;Serine protease 7;Transmembrane protease serine 15;[Cleaved into: Enteropeptidase non-catalytic heavy chain;Enteropeptidase catalytic light chain]

基因ID-1

5651

SwissProt

P98073

背景

catalytic activity:Activation of trypsinogen by selective cleavage of 6-Lys-|-Ile-7 bond.,disease:Defects in PRSS7 are a cause of enterokinase deficiency [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.,function:Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.,PTM:The chains are derived from a single precursor that is cleaved by a trypsin-like protease.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 MAM domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SEA domain.,similarity:Contains 1 SRCR domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 LDL-receptor class A domains.,subunit:Heterodimer of a catalytic (light) chain and a multidomain (heavy) chain linked by a disulfide bond.,tissue specificity:Intestinal brush border.,

细胞定位

Membrane ; Single-pass type II membrane protein .