ITGA3 (heavy chain, Cleaved-Phe33) rabbit pAb

产品详情

产品名称

ITGA3 (heavy chain, Cleaved-Phe33) rabbit pAb

产品货号

YM-A04014

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IF,ELISA,IHC

分子量

93kD,115kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IF/ICC1:50-200;ELISA 1:2000-20000;IHC 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human ITGA3 (heavy chain, Cleaved-Phe33)

特异性

This antibody detects endogenous levels of Human,Mouse,Rat ITGA3 (heavy chain, Cleaved-Phe33, protein was cleaved amino acid sequence between 32-33 )

基因名称

ITGA3 MSK18

蛋白名称

ITGA3 (heavy chain, Cleaved-Phe33)

别名

Integrin alpha-3;CD49 antigen-like family member C;FRP-2;Galactoprotein B3;GAPB3;VLA-3 subunit alpha;CD antigen CD49c;[Cleaved into: Integrin alpha-3 heavy chain;Integrin alpha-3 light chain]

基因ID-1

3675

SwissProt

P26006

背景

integrin subunit alpha 3(ITGA3) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor . Cell projection, invadopodium membrane ; Single-pass type I membrane protein . Cell projection, filopodium membrane ; Single-pass type I membrane protein . Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner. .