ITGA5 (heavy chain, Cleaved-Arg894) rabbit pAb

产品详情

产品名称

ITGA5 (heavy chain, Cleaved-Arg894) rabbit pAb

产品货号

YM-A04015

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA,IHC

分子量

94kD,110kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human ITGA5 (heavy chain, Cleaved-Arg894)

特异性

This antibody detects endogenous levels of Human,Mouse ITGA5 (heavy chain, Cleaved-Arg894, protein was cleaved amino acid sequence between 894-895 )

基因名称

ITGA5 FNRA

蛋白名称

ITGA5 (heavy chain, Cleaved-Arg894)

别名

Integrin alpha-5;CD49 antigen-like family member E;Fibronectin receptor subunit alpha;Integrin alpha-F;VLA-5;CD antigen CD49e;[Cleaved into: Integrin alpha-5 heavy chain;Integrin alpha-5 light chain]

基因ID-1

3678

SwissProt

P08648

背景

function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,

细胞定位

Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .