ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb

产品详情

产品名称

ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb

产品货号

YM-A04021

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC

分子量

16kD,110kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human ITGA2B (light chain form 1, Cleaved-Gln891)

特异性

This antibody detects endogenous levels of Human ITGA2B (light chain form 1, Cleaved-Gln891, protein was cleaved amino acid sequence between 890-891 ). It doesn't recognize light chain form 2

基因名称

ITGA2B GP2B ITGAB

蛋白名称

ITGA2B (light chain form 1, Cleaved-Gln891)

别名

Integrin alpha-IIb;GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD antigen CD41;[Cleaved into: Integrin alpha-IIb heavy chain;Integrin alpha-IIb light chain, form 1;Integrin alpha-IIb light chain, form 2]

基因ID-1

3674

SwissProt

P08514

背景

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],

细胞定位

Membrane; Single-pass type I membrane protein.