MMP7 (Cleaved-Tyr95) rabbit pAb

产品详情

产品名称

MMP7 (Cleaved-Tyr95) rabbit pAb

产品货号

YM-A04038

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA,IHC

分子量

19kD,29kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human MMP7 (Cleaved-Tyr95)

特异性

This antibody detects endogenous levels of Human,Mouse,Rat MMP7 (Cleaved-Tyr95, protein was cleaved amino acid sequence between 94-95 )

基因名称

MMP7 MPSL1 PUMP1

蛋白名称

MMP7 (Cleaved-Tyr95)

别名

Matrilysin;Matrin;Matrix metalloproteinase-7;MMP-7;Pump-1 protease;Uterine metalloproteinase;

基因ID-1

4316

SwissProt

P09237

背景

catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,

细胞定位

Secreted, extracellular space, extracellular matrix .