PROC (light chain, Cleaved-Leu179) rabbit pAb

产品详情

产品名称

PROC (light chain, Cleaved-Leu179) rabbit pAb

产品货号

YM-A04054

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA,IHC

分子量

17kD,45kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)

特异性

This antibody detects endogenous levels of Human PROC (light chain, Cleaved-Leu179, protein was cleaved amino acid sequence between 179-180 )

基因名称

PROC

蛋白名称

PROC (light chain, Cleaved-Leu179)

别名

Vitamin K-dependent protein C;Anticoagulant protein C;Autoprothrombin IIA;Blood coagulation factor XIV;[Cleaved into: Vitamin K-dependent protein C light chain;Vitamin K-dependent protein C heavy chain;Activation peptide]

基因ID-1

5624

SwissProt

P04070

背景

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],

细胞定位

Secreted . Golgi apparatus . Endoplasmic reticulum .