Tubulin α (Acetyl Lys112) Polyclonal Antibody

产品详情

产品名称

Tubulin α (Acetyl Lys112) Polyclonal Antibody

产品货号

YM-A04148

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

50kD

宿主

Rabbit

同种型

IgG

修饰

Acetyl

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized acetyl-peptide derived from human Tubulin α around the acetylation site of K112.

特异性

Acetyl-Tubulin α (K112) Polyclonal Antibody detects endogenous levels of Tubulin α protein only when acetylated at K112.

基因名称

TUBA1A/TUBA1B/TUBA1C

蛋白名称

Tubulin alpha-1A chain/Tubulin alpha-1B chain/Tubulin alpha-1C chain

别名

TUBA1A;TUBA3;Tubulin alpha-1A chain;Alpha-tubulin 3;Tubulin B-alpha-1;Tubulin alpha-3 chain;TUBA1B;Tubulin alpha-1B chain;Alpha-tubulin ubiquitousTubulin K-alpha-1;Tubulin alpha-ubiquitous chain;TUBA1C;TUBA6;Tubulin alpha-1C chain;Alpha-tubulin 6;Tubulin alpha-6 chain

基因ID-1

7846;10376;84790

SwissProt

Q71U36;P68363;Q9BQE3

背景

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

细胞定位

Cytoplasm, cytoskeleton.