FoxO4 (Acetyl Lys189) Polyclonal Antibody

产品详情

产品名称

FoxO4 (Acetyl Lys189) Polyclonal Antibody

产品货号

YM-A04181

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA

分子量

55kD

宿主

Rabbit

同种型

IgG

修饰

Acetyl

推荐稀释比

WB 1:500-2000;ELISA 1:10000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic Acetyl peptide from human protein at AA range: 189

特异性

The antibody detects endogenous FoxO4 when Acetyl occurs at Lys189

基因名称

FOXO4 AFX AFX1 MLLT7

蛋白名称

Forkhead box protein O4 (Fork head domain transcription factor AFX1)

别名

Forkhead box protein O4;Fork head domain transcription factor AFX1;

基因ID-1

4303

SwissProt

P98177

背景

This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],

细胞定位

Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.