HNF-4α (Acetyl Lys106) Polyclonal Antibody

产品详情

产品名称

HNF-4α (Acetyl Lys106) Polyclonal Antibody

产品货号

YM-A04184

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

WB,ELISA

分子量

55kD

宿主

Rabbit

同种型

IgG

修饰

Acetyl

推荐稀释比

WB 1:500-2000;ELISA 1:10000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic Acetyl peptide from human protein at AA range: 106

特异性

The antibody detects endogenous HNF-4α when Acetyl occurs at Lys106

基因名称

HNF4A HNF4 NR2A1 TCF14

蛋白名称

Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)

别名

Hepatocyte nuclear factor 4-alpha;HNF-4-alpha;Nuclear receptor subfamily 2 group A member 1;Transcription factor 14;TCF-14;Transcription factor HNF-4;

基因ID-1

3172

SwissProt

P41235

背景

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],

细胞定位

Nucleus.