c-Myb (Acetyl Lys471) rabbit pAb

产品详情

产品名称

c-Myb (Acetyl Lys471) rabbit pAb

产品货号

YM-A04260

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

70kD

宿主

Rabbit

同种型

IgG

修饰

Acetyl

推荐稀释比

WB 1:1000-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human c-Myb (Acetyl Lys471)

特异性

This antibody detects endogenous levels of Human,Mouse c-Myb (Acetyl Lys471)

基因名称

MYB

蛋白名称

c-Myb (Acetyl Lys471)

别名

Transcriptional activator Myb;Proto-oncogene c-Myb;

基因ID-1

4602

SwissProt

P10242

背景

domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,

细胞定位

Nucleus .