ApoA-V(ab) Monoclonal Antibody

产品详情

产品名称

ApoA-V(ab) Monoclonal Antibody

产品货号

YM-A04322

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ab

免疫原

Purified recombinant fragment of human ApoA-V expressed in E. Coli.

特异性

ApoA-V(ab) Monoclonal Antibody detects endogenous levels of ApoA-V(ab) protein.

基因名称

APOA5

蛋白名称

Apolipoprotein A-V

别名

APOA5;RAP3;Apolipoprotein A-V;Apo-AV;ApoA-V;Apolipoprotein A5;Regeneration-associated protein 3

基因ID-1

116519

SwissProt

Q6Q788

背景

The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009],

细胞定位

Secreted . Early endosome . Late endosome . Golgi apparatus, trans-Golgi network . In the presence of SORL1, internalized to early endosomes, sorted in a retrograde fashion to late endosomes, from which a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network. .