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产品详情
产品名称
C/EBP β Monoclonal Antibody
产品货号
YM-A04360
规格
50μL;100μL
种属反应
Human
实验应用
WB,Flow Cyt,ELISA
分子量
宿主
Mouse
同种型
修饰
Unmodified
推荐稀释比
WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
Monoclonal
克隆号
免疫原
Purified recombinant fragment of human C/EBP β expressed in E. Coli.
特异性
C/EBP β Monoclonal Antibody detects endogenous levels of C/EBP β protein.
基因名称
CEBPB
蛋白名称
CCAAT/enhancer-binding protein beta
别名
CEBPB;LAP;TCF5;PP9092;CCAAT/enhancer-binding protein beta;C/EBP beta;Liver activator protein;Nuclear factor NF-IL6;Transcription factor 5;TCF-5
基因ID-1
1051
SwissProt
P17676
背景
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013],
细胞定位
Nucleus . Cytoplasm . Translocates to the nucleus when phosphorylated at Ser-288. In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity). .
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