CD105 Monoclonal Antibody

产品详情

产品名称

CD105 Monoclonal Antibody

产品货号

YM-A04374

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,Flow Cyt,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human CD105 expressed in E. Coli.

特异性

CD105 Monoclonal Antibody detects endogenous levels of CD105 protein.

基因名称

ENG

蛋白名称

Endoglin

别名

ENG;END;Endoglin;CD antigen CD105

基因ID-1

2022

SwissProt

P17813

背景

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],

细胞定位

Cell membrane ; Single-pass type I membrane protein .