CD247 Monoclonal Antibody(4B10)

产品详情

产品名称

CD247 Monoclonal Antibody(4B10)

产品货号

YM-A04385

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,Flow Cyt,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

4B10

免疫原

Purified recombinant fragment of human CD247 expressed in E. Coli.

特异性

CD247 Monoclonal Antibody detects endogenous levels of CD247 protein.

基因名称

CD247

蛋白名称

T-cell surface glycoprotein CD3 zeta chain

别名

CD247;CD3Z;T3Z;TCRZ;T-cell surface glycoprotein CD3 zeta chain;T-cell receptor T3 zeta chain;CD antigen CD247

基因ID-1

919

SwissProt

P20963

背景

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Single-pass type I membrane protein.