CD276 Monoclonal Antibody

产品详情

产品名称

CD276 Monoclonal Antibody

产品货号

YM-A04386

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,Flow Cyt,ELISA

分子量

100kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human CD276 expressed in E. Coli.

特异性

CD276 Monoclonal Antibody detects endogenous levels of CD276 protein.

基因名称

CD276

蛋白名称

CD276 antigen

别名

CD276;B7H3;PSEC0249;CD276 antigen;4Ig-B7-H3;B7 homolog 3;B7-H3;Costimulatory molecule;CD antigen CD276

基因ID-1

80381

SwissProt

Q5ZPR3

背景

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

细胞定位

Membrane ; Single-pass type I membrane protein .