Chitotriosidase Monoclonal Antibody

产品详情

产品名称

Chitotriosidase Monoclonal Antibody

产品货号

YM-A04409

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of Chitotriosidase (aa22-137) expressed in E. Coli.

特异性

Chitotriosidase Monoclonal Antibody detects endogenous levels of Chitotriosidase protein.

基因名称

CHIT1

蛋白名称

Chitotriosidase-1

别名

CHIT1;Chitotriosidase-1;Chitinase-1

基因ID-1

1118

SwissProt

Q13231

背景

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012],

细胞定位

Secreted. Lysosome. A small proportion is lysosomal.