Crk-L Monoclonal Antibody

产品详情

产品名称

Crk-L Monoclonal Antibody

产品货号

YM-A04419

规格

50μL;100μL

种属反应

Human

实验应用

WB,Flow Cyt,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human Crk-L expressed in E. Coli.

特异性

Crk-L Monoclonal Antibody detects endogenous levels of Crk-L protein.

基因名称

CRKL

蛋白名称

Crk-like protein

别名

CRKL;Crk-like protein

基因ID-1

1399

SwissProt

P46109

背景

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009],

细胞定位

endosome,cytosol,cell-cell adherens junction,extracellular exosome,