EGF Monoclonal Antibody

产品详情

产品名称

EGF Monoclonal Antibody

产品货号

YM-A04445

规格

50μL;100μL

种属反应

Human

实验应用

WB,IF,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human EGF expressed in E. Coli.

特异性

EGF Monoclonal Antibody detects endogenous levels of EGF protein.

基因名称

EGF

蛋白名称

Pro-epidermal growth factor

别名

EGF;Pro-epidermal growth factor;EGF

基因ID-1

1950

SwissProt

P01133

背景

This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],

细胞定位

Membrane; Single-pass type I membrane protein.