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产品详情
产品名称
GDF-8 Monoclonal Antibody
产品货号
YM-A04509
规格
50μL;100μL
种属反应
Human
实验应用
WB,ELISA
分子量
宿主
Mouse
同种型
修饰
Unmodified
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
Monoclonal
克隆号
免疫原
Purified recombinant fragment of GDF-8 expressed in E. Coli.
特异性
GDF-8 Monoclonal Antibody detects endogenous levels of GDF-8 protein.
基因名称
MSTN
蛋白名称
Growth/differentiation factor 8
别名
MSTN;GDF8;Growth/differentiation factor 8;GDF-8;Myostatin
基因ID-1
2660
SwissProt
O14793
背景
myostatin(MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],
细胞定位
Secreted .
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