GKLF Monoclonal Antibody

产品详情

产品名称

GKLF Monoclonal Antibody

产品货号

YM-A04512

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human GKLF expressed in E. Coli.

特异性

GKLF Monoclonal Antibody detects endogenous levels of GKLF protein.

基因名称

KLF4

蛋白名称

Krueppel-like factor 4

别名

KLF4;EZF;GKLF;Krueppel-like factor 4;Epithelial zinc finger protein EZF;Gut-enriched krueppel-like factor

基因ID-1

9314

SwissProt

O43474

背景

This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],

细胞定位

Nucleus.