HFE Monoclonal Antibody

产品详情

产品名称

HFE Monoclonal Antibody

产品货号

YM-A04528

规格

50μL;100μL

种属反应

Human

实验应用

WB,IF,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human HFE expressed in E. Coli.

特异性

HFE Monoclonal Antibody detects endogenous levels of HFE protein.

基因名称

HFE

蛋白名称

Hereditary hemochromatosis protein

别名

HFE;HLAH;Hereditary hemochromatosis protein;HLA-H

基因ID-1

3077

SwissProt

Q30201

背景

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Single-pass type I membrane protein .