LMP7A Monoclonal Antibody

产品详情

产品名称

LMP7A Monoclonal Antibody

产品货号

YM-A04595

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,IHC,IF,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human LMP7A expressed in E. Coli.

特异性

LMP7A Monoclonal Antibody detects endogenous levels of LMP7A protein.

基因名称

PSMB8

蛋白名称

Proteasome subunit beta type-8

别名

PSMB8;LMP7;PSMB5i;RING10;Y2;Proteasome subunit beta type-8;Low molecular mass protein 7;Macropain subunit C13;Multicatalytic endopeptidase complex subunit C13;Proteasome component C13;Proteasome subunit beta-5i;Really interesting

基因ID-1

5696

SwissProt

P28062

背景

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immu

细胞定位

Cytoplasm . Nucleus .