N-CoR Monoclonal Antibody

产品详情

产品名称

N-CoR Monoclonal Antibody

产品货号

YM-A04632

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of N-CoR (aa1-192) expressed in E. Coli.

特异性

N-CoR Monoclonal Antibody detects endogenous levels of N-CoR protein.

基因名称

NCOR1

蛋白名称

Nuclear receptor corepressor 1

别名

NCOR1;KIAA1047;Nuclear receptor corepressor 1;N-CoR;N-CoR1

基因ID-1

9611

SwissProt

O75376

背景

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010],

细胞定位

Nucleus .