PAR4 Monoclonal Antibody

产品详情

产品名称

PAR4 Monoclonal Antibody

产品货号

YM-A04655

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of PAR4 (aa1-330) expressed in E. Coli.

特异性

PAR4 Monoclonal Antibody detects endogenous levels of PAR4 protein.

基因名称

PAWR

蛋白名称

PRKC apoptosis WT1 regulator protein

别名

PAWR;PAR4;PRKC apoptosis WT1 regulator protein;Prostate apoptosis response 4 protein;Par-4

基因ID-1

5074

SwissProt

Q96IZ0

背景

The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm. Nucleus. Mainly cytoplasmic in absence of apoptosis signal and in normal cells. Nuclear in most cancer cell lines. Nuclear entry seems to be essential but not sufficient for apoptosis (By similarity). Nuclear localization includes nucleoplasm and PML nuclear bodies. .