PDK1 Monoclonal Antibody

产品详情

产品名称

PDK1 Monoclonal Antibody

产品货号

YM-A04663

规格

50μL;100μL

种属反应

Human,Rat,Monkey

实验应用

WB,IHC,IF,Flow Cyt,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human PDK1 expressed in E. Coli.

特异性

PDK1 Monoclonal Antibody detects endogenous levels of PDK1 protein.

基因名称

PDK1

蛋白名称

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 mitochondrial

别名

PDK1;PDHK1;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;mitochondrial;Pyruvate dehydrogenase kinase isoform 1

基因ID-1

5163

SwissProt

Q15118

背景

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],

细胞定位

Mitochondrion matrix .