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产品详情
产品名称
Ron Monoclonal Antibody
产品货号
YM-A04697
规格
50μL;100μL
种属反应
Human
实验应用
WB,ELISA
分子量
宿主
Mouse
同种型
修饰
Unmodified
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
Monoclonal
克隆号
免疫原
Purified recombinant fragment of human Ron (aa210-320) expressed in E. Coli.
特异性
Ron Monoclonal Antibody detects endogenous levels of Ron protein.
基因名称
MST1R
蛋白名称
Macrophage-stimulating protein receptor
别名
MST1R;PTK8;RON;Macrophage-stimulating protein receptor;MSP receptor;CDw136;Protein-tyrosine kinase 8;p185-Ron;CD antigen CD136
基因ID-1
4486
SwissProt
Q04912
背景
This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016],
细胞定位
Membrane; Single-pass type I membrane protein.
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