ROR1 Monoclonal Antibody

产品详情

产品名称

ROR1 Monoclonal Antibody

产品货号

YM-A04698

规格

50μL;100μL

种属反应

Human

实验应用

WB,IF,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells

特异性

ROR1 Monoclonal Antibody detects endogenous levels of ROR1 protein.

基因名称

ROR1

蛋白名称

Tyrosine-protein kinase transmembrane receptor ROR1

别名

ROR1;NTRKR1;Tyrosine-protein kinase transmembrane receptor ROR1;Neurotrophic tyrosine kinase;receptor-related 1

基因ID-1

4919

SwissProt

Q01973

背景

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012],

细胞定位

Membrane ; Single-pass type I membrane protein. Cell projection, axon .