RUNX1 Monoclonal Antibody

产品详情

产品名称

RUNX1 Monoclonal Antibody

产品货号

YM-A04704

规格

50μL;100μL

种属反应

Human

实验应用

WB,IF,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Synthesized peptide of human RUNX1.

特异性

RUNX1 Monoclonal Antibody detects endogenous levels of RUNX1 protein.

基因名称

RUNX1

蛋白名称

Runt-related transcription factor 1

别名

RUNX1;AML1;CBFA2;Runt-related transcription factor 1;Acute myeloid leukemia 1 protein;Core-binding factor subunit alpha-2;CBF-alpha-2;Oncogene AML-1;Polyomavirus enhancer-binding protein 2 alpha B subunit;PEA2-alpha B;PEBP2-alpha

基因ID-1

861

SwissProt

Q01196

背景

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus.