SOD-1 Monoclonal Antibody

产品详情

产品名称

SOD-1 Monoclonal Antibody

产品货号

YM-A04720

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IF,Flow Cyt,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of human SOD-1 expressed in E. Coli.

特异性

SOD-1 Monoclonal Antibody detects endogenous levels of SOD-1 protein.

基因名称

SOD1

蛋白名称

Superoxide dismutase [Cu-Zn]

别名

SOD1;Superoxide dismutase [Cu-Zn];Superoxide dismutase 1;hSod1

基因ID-1

6647

SwissProt

P00441

背景

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm . Mitochondrion . Nucleus . Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria. .