TBX5 Monoclonal Antibody

产品详情

产品名称

TBX5 Monoclonal Antibody

产品货号

YM-A04732

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fragment of TBX5 expressed in E. Coli.

特异性

TBX5 Monoclonal Antibody detects endogenous levels of TBX5 protein.

基因名称

TBX5

蛋白名称

T-box transcription factor TBX5

别名

TBX5;T-box transcription factor TBX5;T-box protein 5

基因ID-1

6910

SwissProt

Q99593

背景

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Cytoplasm . Shuttles between the cytoplasm and the nucleus. Acetylation at Lys-339 promotes nuclear retention. .