Thioredoxin Monoclonal Antibody

产品详情

产品名称

Thioredoxin Monoclonal Antibody

产品货号

YM-A04736

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant fusion protein with Thioredoxin tag.

特异性

Thioredoxin Monoclonal Antibody detects endogenous levels of Thioredoxin protein.

基因名称

TXN

蛋白名称

Thioredoxin

别名

TXN;TRDX;TRX;TRX1;Thioredoxin;Trx;ATL-derived factor;ADF;Surface-associated sulphydryl protein;SASP

基因ID-1

7295

SwissProt

P10599

背景

The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

细胞定位

Nucleus . Cytoplasm . Secreted . Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947). .