PPAR-γ Monoclonal Antibody

产品详情

产品名称

PPAR-γ Monoclonal Antibody

产品货号

YM-A04818

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Bovine,Dog,Goat,Pig,Rabbit,sheep

实验应用

WB,IF

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000-1:2000;IF 1:100-1:500;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human PPAR-γ (C-terminus) protein fragments expressed in E.coli.

特异性

PPAR-γ Monoclonal Antibody detects endogenous levels of PPAR-γ protein.

基因名称

PPARG

蛋白名称

Peroxisome proliferator-activated receptor gamma

别名

PPARG;NR1C3;Peroxisome proliferator-activated receptor gamma;PPAR-gamma;Nuclear receptor subfamily 1 group C member 3

基因ID-1

5468

SwissProt

P37231

背景

peroxisome proliferator activated receptor gamma(PPARG) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus. Cytoplasm. Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner. NOCT enhances its nuclear translocation.