TBL1XR1 Monoclonal Antibody

产品详情

产品名称

TBL1XR1 Monoclonal Antibody

产品货号

YM-A04835

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Bovine,Chicken,Dog,Pig,Zebrafish

实验应用

WB,IHC,IF

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:100-1:500;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

Affinity purification

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human TBL1XR1 protein fragments expressed in E.coli.

特异性

TBL1XR1 Monoclonal Antibody detects endogenous levels of TBL1XR1 protein.

基因名称

TBL1XR1

蛋白名称

F-box-like/WD repeat-containing protein TBL1XR1

别名

TBL1XR1;IRA1;TBLR1;F-box-like/WD repeat-containing protein TBL1XR1;Nuclear receptor corepressor/HDAC3 complex subunit TBLR1;TBL1-related protein 1;Transducin beta-like 1X-related protein 1

基因ID-1

79718

SwissProt

Q9BZK7

背景

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016],

细胞定位

Nucleus .