TFIIB mouse mAb

产品详情

产品名称

TFIIB mouse mAb

产品货号

YM-A04851

规格

50μL;100μL

种属反应

Human,Mouse,Monkey

实验应用

WB

分子量

34kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human TFIIB protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of TFIIB and does not cross-react with related proteins.

基因名称

gtf2b

蛋白名称

别名

General transcription factor IIB;General transcription factor TFIIB;gtf2b;RNA polymerase II transcription factor IIB;S300 II;S300-II;TF IIB;TF2B;TF2B_HUMAN;TFIIB;Transcription initiation factor IIB.

基因ID-1

2959

SwissProt

Q00403

背景

general transcription factor IIB(GTF2B) Homo sapiens This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Chromosome . Non-acetylated form colocalizes with DNA in the G0/1, S and G2 phases of the cell cycle, but not during mitosis (PubMed:24441171). Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase, anaphase, and telophase phases of the cell cycle (PubMed:24441171). .