POU5F1/OCT4 mouse mAb

产品详情

产品名称

POU5F1/OCT4 mouse mAb

产品货号

YM-A04860

规格

50μL;100μL

种属反应

Mouse

实验应用

WB

分子量

45kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant mouse POU5F1/OCT4 protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of POU5F1/OCT4 and does not cross-react with related proteins.

基因名称

pou5f1

蛋白名称

别名

MGC22487;Oct 3;Oct 4;Oct-3;Oct-4;OCT3;Oct4;Octamer binding protein 3;Octamer binding protein 4;Octamer binding transcription factor 3;Octamer-binding protein 3;Octamer-binding protein 4;Octamer-binding transcription factor 3;OTF 3;OTF 4;OTF-3;OTF3;OTF4;PO5F1_HUMAN;POU class 5 homeobox 1;POU domain class 5 transcription factor 1;POU domain transcription factor OCT4;POU domain, class 5, transcription factor 1;POU5F1.

基因ID-1

18999

SwissProt

Q01860

背景

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013],

细胞定位

Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. .