CHD3(C-term) mouse mAb

产品详情

产品名称

CHD3(C-term) mouse mAb

产品货号

YM-A04880

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ICC,IP

分子量

260kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000;ICC 1:400

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human CHD3 (C-terminus) protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of CHD3 (C-terminus) and does not cross-react with related proteins.

基因名称

chd3

蛋白名称

别名

226;2600010P09Rik;AF020312;ATP dependent helicase CHD3;ATP-dependent helicase Chd3;CHD-3;Chd3;CHD3_HUMAN;Chd7;Chromodomain-helicase-DNA-binding protein 3;hZFH;MGC40857;Mi 2 autoantigen 240 kDa protein;Mi 2a;Mi-2 autoantigen 240 kDa protein;Mi2 ALPHA;Mi2-alpha;Prp7;Prp9 1;ZFH;Zinc finger helicase;zinc-finger helicase;Snf2-like;.

基因ID-1

1107

SwissProt

Q12873

背景

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus, PML body . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with centrosomes in interphase and mitosis. .