ATP-Citrate Lyase(C-term) mouse mAb

产品详情

产品名称

ATP-Citrate Lyase(C-term) mouse mAb

产品货号

YM-A04887

规格

50μL;100μL

种属反应

Human,Mouse,Monkey

实验应用

WB,ICC,FC

分子量

120kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000;ICC 1:150;Flow Cyt 1:100

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human ATP-Citrate Lyase protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of ATP-Citrate Lyase and does not cross-react with related proteins.

基因名称

acly

蛋白名称

别名

ACL;Acly;ACLY_HUMAN;ATP citrate;pro-S;lyase;ATP citrate lyase;ATP citrate synthase;ATP-citrate;pro-S-;-lyase;ATP-citrate synthase;ATPcitrate synthase;ATPCL;Citrate cleavage enzyme;CLATP;OTTHUMP00000164773.

基因ID-1

47

SwissProt

P53396

背景

ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],

细胞定位

Cytoplasm, cytosol .