Angiotensin Converting Enzyme 1 mouse mAb

产品详情

产品名称

Angiotensin Converting Enzyme 1 mouse mAb

产品货号

YM-A04895

规格

50μL;100μL

种属反应

Mouse

实验应用

WB

分子量

190kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human Angiotensin Converting Enzyme 1 protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of Angiotensin Converting Enzyme 1 and does not cross-react with related proteins.

基因名称

ace

蛋白名称

别名

ACE 1;ACE;ACE T;ACE_HUMAN;ACE1;Angiotensin converting enzyme somatic isoform;Angiotensin converting enzyme testis specific isoform;Angiotensin I converting enzyme;Angiotensin I converting enzyme 1;Angiotensin I converting enzyme peptidyl dipeptidase A 1;Angiotensin-converting enzyme;Carboxycathepsin;CD 143;CD143;CD143 antigen;DCP 1;DCP;DCP1;Dipeptidyl carboxypeptidase 1;Dipeptidyl carboxypeptidase I;Kininase II;MGC26566;MVCD3;Peptidase P;Peptidyl dipeptidase A;soluble form;Testicular ECA.

基因ID-1

1636

SwissProt

P12821

背景

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010],

细胞定位

[Angiotensin-converting enzyme, soluble form]: Secreted.; Cell membrane; Single-pass type I membrane protein. Cytoplasm . Detected in both cell membrane and cytoplasm in neurons. .