DR5 mouse mAb

产品详情

产品名称

DR5 mouse mAb

产品货号

YM-A04968

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ICC

分子量

48kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ICC 1:100

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human DR5 protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of DR5 and does not cross-react with related proteins.

基因名称

tnfrsf10b

蛋白名称

别名

Fas like protein;Apoptosis inducing protein TRICK2A/2B;Apoptosis inducing receptor TRAIL R2;CD 262;CD262;CD262 antigen;Cytotoxic TRAIL receptor 2;Death domain containing receptor for TRAIL/Apo 2L;Death domain containing receptor for TRAIL/Apo2L;Death receptor 5;DR 5;DR5;Fas like protein precursor;KILLER;KILLER/DR5;OTTHUMP00000123492;OTTHUMP00000123493;p53 regulated DNA damage inducible cell death receptor;killer;p53 regulated DNA damage inducible cell death receptor;killer;TNF related apoptosis inducing ligand receptor 2;TNF related apoptosis inducing ligand receptor 2;TNF-related apoptosis-inducing ligand receptor 2;TNFRSF10B;TR10B_HUMAN;TRAIL R2;TRAIL receptor 2;TRAIL-R2;TRAILR2;TRANCER;TRICK2;TRICK2A;TRICK2B;TRICKB;Tumor necrosis factor receptor like protein ZTNFR9;Tumor necrosis factor receptor like protein ZTNFR9;Tumor necrosis factor receptor superfamily member 10b;Tumor necrosis factor receptor superfamily, member 10b;ZTNFR9.

基因ID-1

8795

SwissProt

O14763

背景

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009],

细胞定位

Membrane; Single-pass type I membrane protein.