RPA70 mouse mAb

产品详情

产品名称

RPA70 mouse mAb

产品货号

YM-A04984

规格

50μL;100μL

种属反应

Human,Monkey,Mouse,Rat

实验应用

WB,ICC,IP

分子量

70kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000;ICC 1:100

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human RPA70 protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of RPA70 and does not cross-react with related proteins.

基因名称

rpa70

蛋白名称

别名

Dmrpa1;Drosophila Replication Protein A;DRPA;DSSB;HSSB;Human single stranded DNA binding protein;MST075;MSTP075;p70;REPA 1;REPA1;Replication factor A;Replication factor A protein 1;Replication protein A 70 kDa DNA-binding subunit;Replication protein A 70kDa DNA binding subunit;Replication protein A1;70kD;Replication protein A1;70kD;Replication protein A1 70kDa;Replication protein A1;RF A;RF-A protein 1;RFA;RFA1_HUMAN;RP A;RP-A p70;RPA 1;RPA 70;RPA;RPA1;Single stranded binding protein 70;Single stranded DNA binding protein;Single-stranded DNA-binding protein;Ssb70.

基因ID-1

6117

SwissProt

P27694

背景

function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,

细胞定位

Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .