XRCC1 mouse mAb

产品详情

产品名称

XRCC1 mouse mAb

产品货号

YM-A05007

规格

50μL;100μL

种属反应

Human

实验应用

WB

分子量

82kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human XRCC1 protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of XRCC1 and does not cross-react with related proteins.

基因名称

xrcc1

蛋白名称

别名

DNA repair protein XRCC1;RCC;X ray repair complementing defective repair in chinese hamster;X ray repair complementing defective repair in chinese hamster cells 1;X ray Repair Complementing Defective Repair in Chinese Hamster Cells;X ray repair cross complementing protein 1;X ray repair, complementing defective, repair in Chinese hamster;X-ray repair cross-complementing protein 1;XRCC 1;Xrcc1;XRCC1_HUMAN.

基因ID-1

7515

SwissProt

P18887

背景

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .