GADD45α mouse mAb

产品详情

产品名称

GADD45α mouse mAb

产品货号

YM-A05009

规格

50μL;100μL

种属反应

Transfected

实验应用

WB

分子量

22kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human GADD45 α protein expressed in E.coli

特异性

Transfected Only.

基因名称

gadd45a

蛋白名称

别名

DDIT 1;DDIT-1;DDIT1;DNA damage inducible transcript 1;DNA damage-inducible transcript 1 protein;GA45A_HUMAN;GADD45;GADD45A;Growth arrest and DNA damage inducible 45 alpha;Growth arrest and DNA damage inducible alpha;Growth arrest and DNA damage-inducible protein GADD45 alpha.

基因ID-1

1647

SwissProt

P24522

背景

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010],

细胞定位

Nucleus .