E2F-1 mouse mAb

产品详情

产品名称

E2F-1 mouse mAb

产品货号

YM-A05017

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,IF,IP

分子量

60kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:500;ICC 1:100;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

免疫原

Purified recombinant human E2F-1 protein fragments expressed in E.coli.

特异性

This antibody detects endogenous levels of E2F-1 and does not cross-react with related proteins.

基因名称

e2f1

蛋白名称

别名

Dmel\CG6376;Dmel_CG6376;drosE2F1;E;Sev-CycE;3A;E;var;3-93E;E2-promoter binding facto;E2F 1;E2F transcription factor 1;E2F-1;E2f-PA;E2f-PB;E2f-PC;E2F1;E2f1 E2F transcription factor 1;E2F1_HUMAN;Evar;3;164;KIAA4009;l;3;07172;l;3;j3B1;l;3;j3C2;l;3;rM729;mKIAA4009;OTTHUMP00000030661;PBR3;PRB binding protein E2F 1;PRB-binding protein E2F-1;RBAP 1;RBAP-1;RBAP1;RBBP-3;RBBP3;RBP 3;RBP3;Retinoblastoma-associated protein 1;Retinoblastoma-binding protein 3;Transcription factor E2F1.

基因ID-1

1869

SwissProt

Q01094

背景

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media

细胞定位

Nucleus .